Lataa...
Visualization of uracils created by APOBEC3A using UdgX shows colocalization with RPA at stalled replication forks
The AID/APOBEC enzymes deaminate cytosines in single-stranded DNA (ssDNA) and play key roles in innate and adaptive immunity. The resulting uracils cause mutations and strand breaks that inactivate viruses and diversify antibody repertoire. Mutational evidence suggests that two members of this famil...
Tallennettuna:
| Julkaisussa: | Nucleic Acids Res |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2020
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7672425/ https://ncbi.nlm.nih.gov/pubmed/33074285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa845 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|