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Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises

Amyotrophic lateral sclerosis (ALS) is characterized by the progressive degeneration of the motor neurons that innervate muscle, resulting in gradual paralysis and culminating in the inability to breathe or swallow. This neuronal degeneration occurs in a spatiotemporal manner from a point of onset i...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: McAlary, Luke, Chew, Yee Lian, Lum, Jeremy Stephen, Geraghty, Nicholas John, Yerbury, Justin John, Cashman, Neil R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671971/
https://ncbi.nlm.nih.gov/pubmed/33328890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.581907
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