Effect of pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor α modular (SPPARMα), in atherosclerosis model using low density lipoprotein receptor knock-out swine with balloon injury

BACKGROUND: Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor that has key roles of lipid metabolism and inflammation. The PPARα may affects the initiation and progression of atherosclerosis by reducing inflammatory responses. Pemafibrate (K-877) is a novel selective PPARα m...

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Bibliographic Details
Published in:PLoS One
Main Authors: Konishi, Hirokazu, Miyauchi, Katsumi, Onishi, Akira, Suzuki, Shunichi, Fuchimoto, Daiichiro, Shitara, Jun, Endo, Hirohisa, Wada, Hideki, Doi, Shinichiro, Naito, Ryo, Ogita, Manabu, Dohi, Tomotaka, Kasai, Takatoshi, Daida, Hiroyuki
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671509/
https://ncbi.nlm.nih.gov/pubmed/33201888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241195
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