Development of Accelerated Coronary Atherosclerosis Model Using Low Density Lipoprotein Receptor Knock-Out Swine with Balloon Injury

BACKGROUND: Several animal models have facilitated the evaluation and pathological understanding of atherosclerosis, but a definitive animal model of coronary atherosclerosis is not available. We therefore developed low density lipoprotein receptor knockout (LDLR-KO) pigs with hypercholesterolemia,...

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Udgivet i:PLoS One
Main Authors: Ogita, Manabu, Miyauchi, Katsumi, Onishi, Akira, Tsuboi, Shuta, Wada, Hideki, Konishi, Hirokazu, Naito, Ryo, Dohi, Tomotaka, Kasai, Takatoshi, Kojima, Yuko, Schwartz, Robert S., Daida, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025170/
https://ncbi.nlm.nih.gov/pubmed/27631974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163055
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