MR-LDP: a two-sample Mendelian randomization for GWAS summary statistics accounting for linkage disequilibrium and horizontal pleiotropy

The proliferation of genome-wide association studies (GWAS) has prompted the use of two-sample Mendelian randomization (MR) with genetic variants as instrumental variables (IVs) for drawing reliable causal relationships between health risk factors and disease outcomes. However, the unique features o...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:NAR Genom Bioinform
Autori principali: Cheng, Qing, Yang, Yi, Shi, Xingjie, Yeung, Kar-Fu, Yang, Can, Peng, Heng, Liu, Jin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Methods Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671398/
https://ncbi.nlm.nih.gov/pubmed/33575584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa028
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi