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A Novel Method for Mendelian Randomization Analyses With Pleiotropy and Linkage Disequilibrium in Genetic Variants From Individual Data

Mendelian randomization makes use of genetic variants as instrumental variables to eliminate the influence induced by unknown confounders on causal estimation in epidemiology studies. However, with the soaring genetic variants identified in genome-wide association studies, the pleiotropy, and linkag...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Wang, Yuquan, Li, Tingting, Fu, Liwan, Yang, Siqian, Hu, Yue-Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312241/
https://ncbi.nlm.nih.gov/pubmed/34322150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.634394
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