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Increasing accuracy of HLA imputation by a population-specific reference panel in a FinnGen biobank cohort
The HLA genes, the most polymorphic genes in the human genome, constitute the strongest single genetic susceptibility factor for autoimmune diseases, transplantation alloimmunity and infections. HLA imputation via statistical inference of alleles based on single-nucleotide polymorphisms (SNPs) in li...
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| Publié dans: | NAR Genom Bioinform |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7671345/ https://ncbi.nlm.nih.gov/pubmed/33575586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqaa030 |
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