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Repression of PUM1-mediated mRNA decay activates translesion synthesis after DNA damage
Biological roles of Pumilio1 (PUM1) in ubiquitous cells remain unclear. Here we identify 48 degrading target mRNAs by combined analysis of transcriptome-wide mRNA stabilities and the binding of mRNAs. Further analysis revealed that cells respond to DNA damage by inhibiting PUM1-mediated mRNA decay t...
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| Udgivet i: | Mol Cell Oncol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7671024/ https://ncbi.nlm.nih.gov/pubmed/33241107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1812868 |
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