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Unconventional role of RAC1 in MET-driven anchorage-independent tumor growth

We reported that RAC1 is a master regulator of cell migration and anchorage-independent growth, downstream of the oncogenic Receptor Tyrosine Kinase (RTK) MET. RAC1 growth-promoting role is guanosine triphosphatase (GTPase)- and phosphatidylinositol 3-kinase (PI3K)-independent but promotes mammalian...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Hervieu, Alexia, Kermorgant, Stéphanie
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671004/
https://ncbi.nlm.nih.gov/pubmed/33235904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1803029
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