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The Role of PI3K in Met Driven Cancer: A Recap

The Receptor Tyrosine Kinase (RTK) Met, overexpressed or mutated in cancer, plays a major role in cancer progression and represents an attractive target for cancer therapy. However RTK inhibitors can lead to drug resistance, explaining the necessity to develop therapies that target downstream signal...

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Bibliografiske detaljer
Udgivet i:Front Mol Biosci
Main Authors: Hervieu, Alexia, Kermorgant, Stéphanie
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207648/
https://ncbi.nlm.nih.gov/pubmed/30406111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00086
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