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The Role of PI3K in Met Driven Cancer: A Recap

The Receptor Tyrosine Kinase (RTK) Met, overexpressed or mutated in cancer, plays a major role in cancer progression and represents an attractive target for cancer therapy. However RTK inhibitors can lead to drug resistance, explaining the necessity to develop therapies that target downstream signal...

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Detalhes bibliográficos
Publicado no:Front Mol Biosci
Main Authors: Hervieu, Alexia, Kermorgant, Stéphanie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6207648/
https://ncbi.nlm.nih.gov/pubmed/30406111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00086
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