Enhanced MET translation and signaling sustains K-Ras driven proliferation under anchorage-independent growth conditions

Oncogenic K-Ras mutation occurs frequently in several types of cancers including pancreatic and lung cancers. Tumors with K-Ras mutation are resistant to chemotherapeutic drugs as well as molecular targeting agents. Although numerous approaches are ongoing to find effective ways to treat these tumor...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Fujita-Sato, Saori, Galeas, Jacqueline, Truitt, Morgan, Pitt, Cameron, Urisman, Anatoly, Bandyopadhyay, Sourav, Ruggero, Davide, McCormick, Frank
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506276/
https://ncbi.nlm.nih.gov/pubmed/25977330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1623
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