Transcription factor Oct1 protects against hematopoietic stress and promotes acute myeloid leukemia

A better understanding of the development and progression of acute myelogenous leukemia (AML) is necessary to improve patient outcome. Here we define roles for the transcription factor Oct1/Pou2f1 in AML and normal hematopoiesis. Inappropriate reactivation of the CDX2 gene is widely observed in leuk...

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Publicado no:Exp Hematol
Main Authors: Jafek, Jillian L., Shakya, Arvind, Tai, Pei-Yi, Ibarra, Andrea, Kim, Heejoo, Maddox, Jessica, Chumley, Jeffrey, Spangrude, Gerald J., Miles, Rodney R., Kelley, Todd W., Tantin, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670548/
https://ncbi.nlm.nih.gov/pubmed/31295506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2019.07.002
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