Transcription Factor Oct1 Is a Somatic and Cancer Stem Cell Determinant

Defining master transcription factors governing somatic and cancer stem cell identity is an important goal. Here we show that the Oct4 paralog Oct1, a transcription factor implicated in stress responses, metabolic control, and poised transcription states, regulates normal and pathologic stem cell fu...

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Detalhes bibliográficos
Main Authors: Maddox, Jessica, Shakya, Arvind, South, Samuel, Shelton, Dawne, Andersen, Jared N., Chidester, Stephanie, Kang, Jinsuk, Gligorich, Keith M., Jones, David A., Spangrude, Gerald J., Welm, Bryan E., Tantin, Dean
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493455/
https://ncbi.nlm.nih.gov/pubmed/23144633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003048
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