Cerebral Blood Flow–Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia‐Induced Cardiac Arrest in Rats

BACKGROUND: In most post–cardiac arrest patients, the autoregulation mechanism of cerebral blood flow (CBF) is dysregulated. We examined whether recovery of CBF by adjusting mean arterial pressure mitigates post–cardiac arrest neuronal damage. METHODS AND RESULTS: Wistar rats that underwent 8‐minute...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Wang, Chih‐Hung, Chang, Wei‐Tien, Huang, Chien‐Hua, Tsai, Min‐Shan, Liu, Shing‐Hwa, Chen, Wen‐Jone
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670514/
https://ncbi.nlm.nih.gov/pubmed/32552439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.016513
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