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Cerebral Blood Flow–Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia‐Induced Cardiac Arrest in Rats

BACKGROUND: In most post–cardiac arrest patients, the autoregulation mechanism of cerebral blood flow (CBF) is dysregulated. We examined whether recovery of CBF by adjusting mean arterial pressure mitigates post–cardiac arrest neuronal damage. METHODS AND RESULTS: Wistar rats that underwent 8‐minute...

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Dettagli Bibliografici
Pubblicato in:J Am Heart Assoc
Autori principali: Wang, Chih‐Hung, Chang, Wei‐Tien, Huang, Chien‐Hua, Tsai, Min‐Shan, Liu, Shing‐Hwa, Chen, Wen‐Jone
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670514/
https://ncbi.nlm.nih.gov/pubmed/32552439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.016513
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