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Cerebral Blood Flow–Guided Manipulation of Arterial Blood Pressure Attenuates Hippocampal Apoptosis After Asphyxia‐Induced Cardiac Arrest in Rats

BACKGROUND: In most post–cardiac arrest patients, the autoregulation mechanism of cerebral blood flow (CBF) is dysregulated. We examined whether recovery of CBF by adjusting mean arterial pressure mitigates post–cardiac arrest neuronal damage. METHODS AND RESULTS: Wistar rats that underwent 8‐minute...

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Détails bibliographiques
Publié dans:J Am Heart Assoc
Auteurs principaux: Wang, Chih‐Hung, Chang, Wei‐Tien, Huang, Chien‐Hua, Tsai, Min‐Shan, Liu, Shing‐Hwa, Chen, Wen‐Jone
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670514/
https://ncbi.nlm.nih.gov/pubmed/32552439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.120.016513
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