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O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation
O-linked β-N-acetylglucosamine (O-GlcNAc) is a post-translational modification which occurs on the hydroxyl group of serine or threonine residues of nucleocytoplasmic proteins. It has been reported that the presence of this single sugar motif regulates various biological events by altering the fate...
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| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7670456/ https://ncbi.nlm.nih.gov/pubmed/33199824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76862-0 |
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