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O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation
O-linked β-N-acetylglucosamine (O-GlcNAc) is a post-translational modification which occurs on the hydroxyl group of serine or threonine residues of nucleocytoplasmic proteins. It has been reported that the presence of this single sugar motif regulates various biological events by altering the fate...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7670456/ https://ncbi.nlm.nih.gov/pubmed/33199824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76862-0 |
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