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O-GlcNAc stabilizes SMAD4 by inhibiting GSK-3β-mediated proteasomal degradation
O-linked β-N-acetylglucosamine (O-GlcNAc) is a post-translational modification which occurs on the hydroxyl group of serine or threonine residues of nucleocytoplasmic proteins. It has been reported that the presence of this single sugar motif regulates various biological events by altering the fate...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7670456/ https://ncbi.nlm.nih.gov/pubmed/33199824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76862-0 |
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