The Utility of MDM2 and CDK4 Immunohistochemistry and MDM2 FISH in Craniofacial Osteosarcoma

Craniofacial osteosarcoma is rare (2–10% of all osteosarcomas). Most low grade fibroblastic osteosarcomas of the long bones are characterized by amplification of chromosome12q including MDM2 and CDK4 genes. This study aims to investigate the utility of MDM2 and CDK4 immunostains as well as MDM2 FISH...

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Publicado en:Head Neck Pathol
Autores principales: Limbach, Abberly Lott, Lingen, Mark W., McElherne, James, Mashek, Heather, Fitzpatrick, Carrie, Hyjek, Elizabeth, Mostofi, Reza, Cipriani, Nicole A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2020
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Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669933/
https://ncbi.nlm.nih.gov/pubmed/32026294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12105-020-01139-x
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