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The Utility of MDM2 and CDK4 Immunohistochemistry and MDM2 FISH in Craniofacial Osteosarcoma

Craniofacial osteosarcoma is rare (2–10% of all osteosarcomas). Most low grade fibroblastic osteosarcomas of the long bones are characterized by amplification of chromosome12q including MDM2 and CDK4 genes. This study aims to investigate the utility of MDM2 and CDK4 immunostains as well as MDM2 FISH...

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Detalhes bibliográficos
Publicado no:Head Neck Pathol
Main Authors: Limbach, Abberly Lott, Lingen, Mark W., McElherne, James, Mashek, Heather, Fitzpatrick, Carrie, Hyjek, Elizabeth, Mostofi, Reza, Cipriani, Nicole A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669933/
https://ncbi.nlm.nih.gov/pubmed/32026294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12105-020-01139-x
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