The Utility of MDM2 and CDK4 Immunohistochemistry and MDM2 FISH in Craniofacial Osteosarcoma

Craniofacial osteosarcoma is rare (2–10% of all osteosarcomas). Most low grade fibroblastic osteosarcomas of the long bones are characterized by amplification of chromosome12q including MDM2 and CDK4 genes. This study aims to investigate the utility of MDM2 and CDK4 immunostains as well as MDM2 FISH...

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Publicat a:Head Neck Pathol
Autors principals: Limbach, Abberly Lott, Lingen, Mark W., McElherne, James, Mashek, Heather, Fitzpatrick, Carrie, Hyjek, Elizabeth, Mostofi, Reza, Cipriani, Nicole A.
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2020
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669933/
https://ncbi.nlm.nih.gov/pubmed/32026294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12105-020-01139-x
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