The Utility of MDM2 and CDK4 Immunohistochemistry and MDM2 FISH in Craniofacial Osteosarcoma

Craniofacial osteosarcoma is rare (2–10% of all osteosarcomas). Most low grade fibroblastic osteosarcomas of the long bones are characterized by amplification of chromosome12q including MDM2 and CDK4 genes. This study aims to investigate the utility of MDM2 and CDK4 immunostains as well as MDM2 FISH...

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Detaylı Bibliyografya
Yayımlandı:Head Neck Pathol
Asıl Yazarlar: Limbach, Abberly Lott, Lingen, Mark W., McElherne, James, Mashek, Heather, Fitzpatrick, Carrie, Hyjek, Elizabeth, Mostofi, Reza, Cipriani, Nicole A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer US 2020
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669933/
https://ncbi.nlm.nih.gov/pubmed/32026294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12105-020-01139-x
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