Tumor Necrosis Factor Alpha (TNF-α) Blockade improves Natural Killer Cell (NK) Activation, Hypertension, and Mitochondrial Oxidative Stress in a Preclinical Rat Model of Preeclampsia

Preeclampsia (PE) is associated with placental ischemia, hypertension (MAP), increased cytolytic natural killer (cNK) cells, tumor necrosis factor alpha (TNF-α) and mitochondrial Reactive Oxygen Species (mt ROS). The reduced uterine perfusion pressure (RUPP) rat model of PE, exhibits many characteri...

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Опубликовано в: :Hypertens Pregnancy
Главные авторы: Cunningham, Mark W, Jayaram, Aswathi, Deer, Evangeline, Amaral, Lorena M., Vaka, Venkata Ramana, Ibrahim, Tarek, Cornelius, Denise C., LaMarca, Babbette
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669709/
https://ncbi.nlm.nih.gov/pubmed/32646252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10641955.2020.1793999
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