Investigation of interleukin-2-mediated changes in blood pressure, fetal growth restriction, and innate immune activation in normal pregnant rats and in a preclinical rat model of preeclampsia

Two important clinical features of preeclampsia (PE) are hypertension and fetal growth restriction. The reduced uterine perfusion pressure (RUPP) preclinical rat model of PE exhibits both of these features. Moreover, RUPP and PE women have elevated vasoconstrictor peptide endothelin-1 (ET-1) and inf...

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Detalhes bibliográficos
Publicado no:Biol Sex Differ
Main Authors: Cunningham, Mark W., Amaral, Lorena M., Campbell, Nathan E., Cornelius, Denise C., Ibrahim, Tarek, Vaka, Venkata Ramana, LaMarca, Babbette
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7789596/
https://ncbi.nlm.nih.gov/pubmed/33407826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13293-020-00345-0
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