Perivascular Mesenchymal Cells Control Adipose Tissue Macrophage Accrual in Obesity

Chronic low-grade white adipose tissue (WAT) inflammation is a hallmark of metabolic syndrome in obesity. Here, we demonstrate that a subpopulation of murine WAT perivascular (PDGFRβ+) cells, termed “fibro-inflammatory progenitors” (FIPs), activate pro-inflammatory signaling cascades shortly after t...

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Dades bibliogràfiques
Publicat a:Nat Metab
Autors principals: Shan, Bo, Shao, Mengle, Zhang, Qianbin, Hepler, Chelsea, Paschoal, Vivian A., Barnes, Spencer D., Vishvanath, Lavanya, An, Yu A., Jia, Lin, Malladi, Venkat S., Strand, Douglas W., Gupta, Olga T., Elmquist, Joel K., Oh, Dayoung, Gupta, Rana K.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669663/
https://ncbi.nlm.nih.gov/pubmed/33139957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-020-00301-7
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