Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice

White adipose tissue (WAT) remodeling is dictated by coordinated interactions between adipocytes and resident stromal-vascular cells; however, the functional heterogeneity of adipose stromal cells has remained unresolved. We combined single-cell RNA-sequencing and FACS to identify and isolate functi...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Hepler, Chelsea, Shan, Bo, Zhang, Qianbin, Henry, Gervaise H, Shao, Mengle, Vishvanath, Lavanya, Ghaben, Alexandra L, Mobley, Angela B, Strand, Douglas, Hon, Gary C, Gupta, Rana K
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Human Biology and Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167054/
https://ncbi.nlm.nih.gov/pubmed/30265241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39636
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