Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice

Visceral adiposity confers significant risk for developing metabolic disease in obesity whereas preferential expansion of subcutaneous white adipose tissue (WAT) appears protective. Unlike subcutaneous WAT, visceral WAT is resistant to adopting a protective thermogenic phenotype characterized by the...

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Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Hepler, Chelsea, Shao, Mengle, Xia, Jonathan Y, Ghaben, Alexandra L, Pearson, Mackenzie J, Vishvanath, Lavanya, Sharma, Ankit X, Morley, Thomas S, Holland, William L, Gupta, Rana K
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
Soggetti:
Human Biology and Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552276/
https://ncbi.nlm.nih.gov/pubmed/28722653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27669
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