Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program

The transcriptional regulators Ebf2 and Prdm16 establish and maintain the brown/beige fat cell identity. However, the mechanisms operating in white adipocytes to suppress the thermogenic gene program and maintain an energy-storing phenotype are less understood. Here, we report that the transcription...

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Pubblicato in:Cell Metab
Autori principali: Shao, Mengle, Ishibashi, Jeff, Kusminski, Christine M., Wang, Qiong A., Hepler, Chelsea, Vishvanath, Lavanya, MacPherson, Karen A., Spurgin, Stephen B., Sun, Kai, Holland, William L., Seale, Patrick, Gupta, Rana K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091077/
https://ncbi.nlm.nih.gov/pubmed/27238639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.04.023
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