Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice

Visceral adiposity confers significant risk for developing metabolic disease in obesity whereas preferential expansion of subcutaneous white adipose tissue (WAT) appears protective. Unlike subcutaneous WAT, visceral WAT is resistant to adopting a protective thermogenic phenotype characterized by the...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Hepler, Chelsea, Shao, Mengle, Xia, Jonathan Y, Ghaben, Alexandra L, Pearson, Mackenzie J, Vishvanath, Lavanya, Sharma, Ankit X, Morley, Thomas S, Holland, William L, Gupta, Rana K
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Assuntos:
Human Biology and Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552276/
https://ncbi.nlm.nih.gov/pubmed/28722653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27669
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