Multiplex immunofluorescence in formalin-fixed paraffin-embedded tumor tissue to identify single cell-level PI3K pathway activation

PURPOSE: Identifying cancers with high PI3K pathway activity is critical for treatment selection and eligibility into clinical trials of PI3K inhibitors. Assessments of tumor signaling pathway activity need to consider intratumoral heterogeneity and multiple regulatory nodes. METHODS: We established...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Clin Cancer Res
Autori principali: Stopsack, Konrad H., Huang, Ying, Tyekucheva, Svitlana, Gerke, Travis A., Bango, Clyde, Elfandy, Habiba, Bowden, Michaela, Penney, Kathryn L., Roberts, Thomas M., Parmigiani, Giovanni, Kantoff, Philip W., Mucci, Lorelei A., Loda, Massimo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669556/
https://ncbi.nlm.nih.gov/pubmed/32913135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2000
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi