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The Higher Sensitivity of GABAergic Compared to Glutamatergic Neurons to Growth-Promoting C3bot Treatment Is Mediated by Vimentin

The current study investigates the neurotrophic effects of Clostridium botulinum C3 transferase (C3bot) on highly purified, glia-free, GABAergic, and glutamatergic neurons. Incubation with nanomolar concentrations of C3bot promotes dendrite formation as well as dendritic and axonal outgrowth in rat...

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Pubblicato in:Front Cell Neurosci
Autori principali: Adolf, Andrej, Turko, Paul, Rohrbeck, Astrid, Just, Ingo, Vida, Imre, Ahnert-Hilger, Gudrun, Höltje, Markus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669547/
https://ncbi.nlm.nih.gov/pubmed/33240046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.596072
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