A Dual Receptor Targeting- and BBB Penetrating- Peptide Functionalized Polyethyleneimine Nanocomplex for Secretory Endostatin Gene Delivery to Malignant Glioma

PURPOSE: Vascular endothelial growth factor receptor 2 (VEGFR-2) and neuropilin-1 (NRP-1) are two prominent synergistic receptors overexpressed on new blood vessels in glioma and may be promising targets for antiglioma therapy. The aim of this study was to design a dual receptor targeting and blood-...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Lu, Lu, Chen, Hongyuan, Wang, Longkun, Zhao, Lin, Cheng, Yanna, Wang, Aijun, Wang, Fengshan, Zhang, Xinke
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7669533/
https://ncbi.nlm.nih.gov/pubmed/33209022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S270208
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