Biodegradable brain-penetrating DNA nanocomplexes and their use to treat malignant brain tumors

The discovery of powerful genetic targets has spurred clinical development of gene therapy approaches to treat patients with malignant brain tumors. However, lack of success in the clinic has been attributed to the inability of conventional gene vectors to achieve gene transfer throughout highly dis...

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Pubblicato in:J Control Release
Autori principali: Mastorakos, Panagiotis, Zhang, Clark, Song, Eric, Kim, Young Eun, Park, Hee Won, Berry, Sneha, Choi, Won Kyu, Hanes, Justin, Suk, Jung Soo
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824426/
https://ncbi.nlm.nih.gov/pubmed/28694032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.07.009
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