Convection enhanced delivery of cisplatin-loaded brain penetrating nanoparticles cures malignant glioma in rats

Glioblastoma multiforme (GBM) is highly invasive and uniformly fatal, with median survival < 20 months after diagnosis even with the most aggressive treatment that includes surgery, radiation, and systemic chemotherapy. Cisplatin is a particularly potent chemotherapeutic agent, but its use to tre...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Control Release
Prif Awduron: Zhang, Clark, Nance, Elizabeth A., Mastorakos, Panagiotis, Chisholm, Jane, Berry, Sneha, Eberhart, Charles, Tyler, Betty, Brem, Henry, Suk, Jung Soo, Hanes, Justin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589496/
https://ncbi.nlm.nih.gov/pubmed/28279797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.03.007
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