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Host genetic liability for severe COVID-19 overlaps with alcohol drinking behavior and diabetic outcomes in over 1 million participants

To distinguish correlation from causation, we performed in-silico analyses of three COVID-19 outcomes (N>1,000,000). We show genetic correlation and putative causality with depressive symptoms, metformin use, and alcohol use. COVID-19 risk loci associated with several hematologic biomarkers. Comp...

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Detalhes bibliográficos
Publicado no:medRxiv
Main Authors: Wendt, Frank R, De Lillo, Antonella, Pathak, Gita A, De Angelis, Flavio, Polimanti, Renato
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668748/
https://ncbi.nlm.nih.gov/pubmed/33200138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.11.08.20227884
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