Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome

Multisystem Inflammatory Syndrome in Children (MIS-C), a hyperinflammatory syndrome associated with SARS-CoV-2 infection, shares many clinical features with toxic shock syndrome, which is triggered by bacterial superantigens. The superantigen specificity for binding different Vβ-chains results in Vβ...

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Опубликовано в: :bioRxiv
Главные авторы: Porritt, Rebecca A, Paschold, Lisa, Noval Rivas, Magali, Hongying Cheng, Mary, Yonker, Lael M, Chandnani, Harsha, Lopez, Merrick, Simnica, Donjete, Schultheiß, Christoph, Santiskulvong, Chintda, Van Eyk, Jennifer, Fasano, Alessio, Bahar, Ivet, Binder, Mascha, Arditi, Moshe
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668738/
https://ncbi.nlm.nih.gov/pubmed/33200133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.11.09.372169
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