A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro

We recently discovered a superantigen-like motif, similar to Staphylococcal enterotoxin B (SEB), near the S1/S2 cleavage site of SARS-CoV-2 Spike protein, which might explain the multisystem-inflammatory syndrome (MIS-C) observed in children and cytokine storm in severe COVID-19 patients. We show he...

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Pubblicato in:bioRxiv
Autori principali: Cheng, Mary Hongying, Porritt, Rebecca A., Rivas, Magali Noval, Krieger, James M, Ozdemir, Asli Beyza, Garcia, Gustavo, Arumugaswami, Vaithilingaraja, Fries, Bettina C., Arditi, Moshe, Bahar, Ivet
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709177/
https://ncbi.nlm.nih.gov/pubmed/33269352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.11.24.395079
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