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AIM2 in health and disease: inflammasome and beyond

Nucleic acid sensing is a critical mechanism by which the immune system monitors for pathogen invasion. A set of germline-encoded innate immune receptors detect microbial DNA in various compartments of the cell, such as endosomes, the cytosol, and the nucleus. Sensing of microbial DNA through these...

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Bibliographic Details
Published in:Immunol Rev
Main Authors: Kumari, Puja, Russo, Ashley J., Shivcharan, Sonia, Rathinam, Vijay A.
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668394/
https://ncbi.nlm.nih.gov/pubmed/32713036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12903
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