Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction

Microglia are the principal phagocytes that clear cell debris in the central nervous system (CNS). This raises the question, which cells remove cell debris when microglial phagocytic activity is impaired. We addressed this question using Siglech (dtr) mice, which enable highly specific ablation of m...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Konishi, Hiroyuki, Okamoto, Takayuki, Hara, Yuichiro, Komine, Okiru, Tamada, Hiromi, Maeda, Mitsuyo, Osako, Fumika, Kobayashi, Masaaki, Nishiyama, Akira, Kataoka, Yosky, Takai, Toshiyuki, Udagawa, Nobuyuki, Jung, Steffen, Ozato, Keiko, Tamura, Tomohiko, Tsuda, Makoto, Yamanaka, Koji, Ogi, Tomoo, Sato, Katsuaki, Kiyama, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667883/
https://ncbi.nlm.nih.gov/pubmed/32959911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104464
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