טוען...
EGFR‐mediated tyrosine phosphorylation of STING determines its trafficking route and cellular innate immunity functions
STING (STimulator of INterferon Genes) mediates protective cellular response to microbial infection and tissue damage, but its aberrant activation can lead to autoinflammatory diseases. Upon ligand stimulation, the endoplasmic reticulum (ER) protein STING translocates to endosomes for induction of i...
שמור ב:
| הוצא לאור ב: | EMBO J |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
John Wiley and Sons Inc.
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7667877/ https://ncbi.nlm.nih.gov/pubmed/32926474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019104106 |
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