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EGFR kinase activity is required for TLR4 signaling and the septic shock response

Mammalian Toll-like receptors (TLR) recognize microbial products and elicit transient immune responses that protect the infected host from disease. TLR4—which signals from both plasma and endosomal membranes—is activated by bacterial lipopolysaccharides (LPS) and induces many cytokine genes, the pro...

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Bibliografski detalji
Izdano u:EMBO Rep
Glavni autori: Chattopadhyay, Saurabh, Veleeparambil, Manoj, Poddar, Darshana, Abdulkhalek, Samar, Bandyopadhyay, Sudip K, Fensterl, Volker, Sen, Ganes C
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641505/
https://ncbi.nlm.nih.gov/pubmed/26341626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540337
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