EGFR kinase activity is required for TLR4 signaling and the septic shock response

Mammalian Toll-like receptors (TLR) recognize microbial products and elicit transient immune responses that protect the infected host from disease. TLR4—which signals from both plasma and endosomal membranes—is activated by bacterial lipopolysaccharides (LPS) and induces many cytokine genes, the pro...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Chattopadhyay, Saurabh, Veleeparambil, Manoj, Poddar, Darshana, Abdulkhalek, Samar, Bandyopadhyay, Sudip K, Fensterl, Volker, Sen, Ganes C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641505/
https://ncbi.nlm.nih.gov/pubmed/26341626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540337
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