EGFR kinase activity is required for TLR4 signaling and the septic shock response

Mammalian Toll-like receptors (TLR) recognize microbial products and elicit transient immune responses that protect the infected host from disease. TLR4—which signals from both plasma and endosomal membranes—is activated by bacterial lipopolysaccharides (LPS) and induces many cytokine genes, the pro...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:EMBO Rep
Päätekijät: Chattopadhyay, Saurabh, Veleeparambil, Manoj, Poddar, Darshana, Abdulkhalek, Samar, Bandyopadhyay, Sudip K, Fensterl, Volker, Sen, Ganes C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley & Sons, Ltd 2015
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641505/
https://ncbi.nlm.nih.gov/pubmed/26341626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540337
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