EGFR kinase activity is required for TLR4 signaling and the septic shock response

Mammalian Toll-like receptors (TLR) recognize microbial products and elicit transient immune responses that protect the infected host from disease. TLR4—which signals from both plasma and endosomal membranes—is activated by bacterial lipopolysaccharides (LPS) and induces many cytokine genes, the pro...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Chattopadhyay, Saurabh, Veleeparambil, Manoj, Poddar, Darshana, Abdulkhalek, Samar, Bandyopadhyay, Sudip K, Fensterl, Volker, Sen, Ganes C
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641505/
https://ncbi.nlm.nih.gov/pubmed/26341626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540337
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