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Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors

[Image: see text] SUMOylation has emerged as an important post-translational modification that has been shown to modulate protein activity associated with various signaling pathways, and consequently, it has emerged as an important therapeutic target. While several natural products have been shown t...

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Опубликовано в: :ACS Med Chem Lett
Главные авторы: Brackett, Christopher M., García-Casas, Ana, Castillo-Lluva, Sonia, Blagg, Brian S. J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2020
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7667826/
https://ncbi.nlm.nih.gov/pubmed/33214832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00353
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