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Maternal sitagliptin treatment attenuates offspring glucose metabolism and intestinal proinflammatory cytokines IL-6 and TNF-α expression in male rats

Increasing evidence shows that maternal overnutrition may increase the risk of diabetes in offspring. We hypothesized that maternal sitagliptin intervention may improve glucose intolerance through gut targeting. Female Sprague-Dawley (SD) rats were fed a normal diet (ND) or a high-fat diet (HFD) for...

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Bibliografiske detaljer
Udgivet i:PeerJ
Main Authors: Zhang, Qian, Xiao, Xinhua, Zheng, Jia, Li, Ming, Yu, Miao, Ping, Fan, Wang, Tong, Wang, Xiaojing
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666563/
https://ncbi.nlm.nih.gov/pubmed/33240638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10310
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