Maternal sitagliptin treatment attenuates offspring glucose metabolism and intestinal proinflammatory cytokines IL-6 and TNF-α expression in male rats

Increasing evidence shows that maternal overnutrition may increase the risk of diabetes in offspring. We hypothesized that maternal sitagliptin intervention may improve glucose intolerance through gut targeting. Female Sprague-Dawley (SD) rats were fed a normal diet (ND) or a high-fat diet (HFD) for...

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I publikationen:PeerJ
Huvudupphovsmän: Zhang, Qian, Xiao, Xinhua, Zheng, Jia, Li, Ming, Yu, Miao, Ping, Fan, Wang, Tong, Wang, Xiaojing
Materialtyp: Artigo
Språk:Inglês
Publicerad: PeerJ Inc. 2020
Ämnen:
Diabetes and Endocrinology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666563/
https://ncbi.nlm.nih.gov/pubmed/33240638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.10310
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