Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging

PURPOSE: Currently, a variety of red and green beetle luciferase variants are available for bioluminescence imaging (BLI). In addition, new luciferin analogues providing longer wavelength luminescence have been developed that show promise for improved deep tissue imaging. However, a detailed assessm...

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Bibliographic Details
Published in:Mol Imaging Biol
Main Authors: Zambito, Giorgia, Gaspar, Natasa, Ridwan, Yanto, Hall, Mary P., Shi, Ce, Kirkland, Thomas A., Encell, Lance P., Löwik, Clemens, Mezzanotte, Laura
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666294/
https://ncbi.nlm.nih.gov/pubmed/32926287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01523-7
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