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Molecular adaptation to calsequestrin 2 (CASQ2) point mutations leading to catecholaminergic polymorphic ventricular tachycardia (CPVT): comparative analysis of R33Q and D307H mutants

Homozygous calsequestrin 2 (CASQ2) point mutations leads to catecholaminergic polymorphic ventricular tachycardia: a common pathogenetic feature appears to be the drastic reduction of mutant CASQ2 in spite of normal transcription. Comparative biochemical analysis of R33Q and D307H knock in mutant mi...

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Detalhes bibliográficos
Publicado no:J Muscle Res Cell Motil
Main Authors: Valle, Giorgia, Arad, Michael, Volpe, Pompeo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666291/
https://ncbi.nlm.nih.gov/pubmed/32902830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-020-09587-2
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