Optimizing catecholaminergic polymorphic ventricular tachycardia therapy in calsequestrin-mutant mice

BACKGROUND: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a lethal arrhythmia provoked by physical or emotional stress and mediated by spontaneous Ca(2+) release and delayed after-depolarizations. Beta-adrenergic blockers are the therapy of choice but fail to control arrhythmia in...

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Main Authors: Katz, Guy, Khoury, Assad, Kurtzwald, Efrat, Hochhauser, Edith, Porat, Eyal, Shainberg, Asher, Seidman, Jonathan G., Seidman, Christine E., Lorber, Abraham, Eldar, Michael, Arad, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103178/
https://ncbi.nlm.nih.gov/pubmed/20620233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2010.07.004
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