On-treatment measurements of circulating tumor DNA during FOLFOX therapy in patients with colorectal cancer

We addressed a significant unknown feature of circulating tumor DNA (ctDNA), i.e., how ctDNA levels change during chemotherapy, by serially monitoring ctDNA in patients with colorectal cancer during the 48-h application of FOLFOX. Surprisingly, we did not observe a spike in ctDNA as a sign of a resp...

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Dettagli Bibliografici
Pubblicato in:NPJ Precis Oncol
Autori principali: Moser, Tina, Waldispuehl-Geigl, Julie, Belic, Jelena, Weber, Sabrina, Zhou, Qing, Hasenleithner, Samantha O., Graf, Ricarda, Terzic, Jasmin Alia, Posch, Florian, Sill, Heinz, Lax, Sigurd, Kashofer, Karl, Hoefler, Gerald, Schoellnast, Helmut, Heitzer, Ellen, Geigl, Jochen B., Bauernhofer, Thomas, Speicher, Michael R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7666126/
https://ncbi.nlm.nih.gov/pubmed/33299124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-020-00134-3
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