MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses

Recent outbreaks of Ebola virus (EBOV) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have exposed our limited therapeutic options for such diseases and our poor understanding of the cellular mechanisms that block viral infections. Using a transposon-mediated gene-activation screen...

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Détails bibliographiques
Publié dans:Science
Auteurs principaux: Bruchez, Anna, Sha, Ky, Johnson, Joshua, Chen, Li, Stefani, Caroline, McConnell, Hannah, Gaucherand, Lea, Prins, Rachel, Matreyek, Kenneth A., Hume, Adam J., Mühlberger, Elke, Schmidt, Emmett V., Olinger, Gene G., Stuart, Lynda M., Lacy-Hulbert, Adam
Format: Artigo
Langue:Inglês
Publié: American Association for the Advancement of Science 2020
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Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7665841/
https://ncbi.nlm.nih.gov/pubmed/32855215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abb3753
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